TRIBULUS TERRESTRIS, ERIC BRAVERMAN,MD

Dr. Eric Braverman, MD in the Oct, 2008 issue of Life Extension Magazine, page 81.
" Extracts of the herb Tribulus Terrestris have also been used to manage the symptoms of low testosterone levels. study quoted McKay ,D Nutrients and botanicals for dysfunction: examing the evidence. Alter. Med Rev. 2004 Mar,9(1) :4-16.

MAGNESIUM THE MINERAL ESSENTIAL TO LIFE, AND TO THE HORMONAL BONE COMPLEX.

Magnesium is used in a pivotal role for more than 300 enzymatic reactions in the human body. This mineral plays a role in neutralizing acid from protein metabolism. First, it is nedded for proper functioning of Vitamin D, second PTH the Parathyroid hormone, and third for calcitonin, these are the three hormones that regulate bone metabolism and your mineral stores."

Source ---- Verbatim quote from James E. Dowd, M.D. F.A.C.R , He is Professor of Medicine at Michigan State University, Founder & Director of Arthritis Institute of Michigan, & Michigan Arthritis Research Center.

RHODIOLA 5% (Rosavins) Adaptogenic Herb

Rhodiola 5% Rosavins---- Plant, Herb, in tea form also, an adapotgenic herb, useful for physical endurance, protein metabolism, helps memory & mental performance, accenuates physical strength, helps insure mobility, increases circulation to the brain, fights depression & emotional stressors. Used in Russia, Siberia, to cope with cold weather & stressfull life, adaptogenic activity,
Increase the basic b- endorphin in blood plasma which inhibits the hormonal change indicative of stress.
Information collected from something called the Internet.

INSOMNIA & UNFAMILAR SLEEPING LOCATION

This double - blind placebo - controlled study found that the administration of L- Tryptophane at doses of 1 gram or 3 grams per night significantly reduced sleep latency in patients suffering from insomnia due to unfamiliar sleeping location.

______ E. Hartman & R. Elion, " The Insomnia of sleeping in a strange Place; Effects of L-Tryptophane", Psychopharmacology, 53(2) July18, 1977, pgs 131- 133.
The above stated journal is the source.

AUTOIMMUNE THYROID DISEASE

"Treatment of Hashimoto's Thyroidits requires life long administration of Thyroid hormone to correct or prevent hypothyroidism. The common replacement is 125-175 mcg - of thyroxine (with or without T3). Many of my patients, do better with Armour (brand) Thyroid".

Wilkinson R., M.D., "Thyroid Dysfunction and treatment",
CME Monograph (Tucson, University of Arizona School of Medicine, 1997). The above clinical publication published by a board certified endocrinologist, Iquote him verbatim. Please note----- Desicated Thyroid: The generic name for tablets of animal Thyroid gland used to treat low Thyroid conditions; ITS ACTIVE INGREDIENTS INCLUDE BOTH T-3 and T -4 Brand name include Armour, Westroid, Naturhroid & Proloid.

MY STATED AIM IS ----------- J.B.

The Alverton Paradigm champions the Neurohormonal-Sleep Paradigm in modern medicine. This paradigm shift is advocated by board -certified Physicians in their field. Their thinking I feel reflects an elegant symetery, that can quite simply save lives and restore Americas health care system. I quote verbatim from peer-review journals, medical researchers, clinicians, books & relevant articles. Why? For the simple apptittude reason that you should consider their work, it could re-invigorate & change your life. Kindly e-mail me at citizenjarv@yahoo.com with a comment or a critique, so lets have a dialoug for Veritas.

Jared Breed.

H-R-T- HORMONE REPLACEMENT THERAPY

HRT- HORMONE REPLACEMENT THERAPY--- This therapy is used for hormone deficiencies , female menopause, Male - andropause, Osteoporosis, mood disorders, fatique, obesity, cognitive deficiencies. The key component of my therapies is the use of NATURAL BIOIDENTICAL HORMONES. These hormones are made from natural sources such as plants, and work by precisely duplicating the bodys original hormones. The bonding of a hormone to its recptor is determined by the shape of the hormone molecule, like a key fits a lock. Synthetic hormones not found in nature like Premarin differ in their molecular configurationn from Endogenous( made in our body) hormones, so they differ in their activity at the receptor level. They will not provide the same total activity as the hormones they are intended to replace. They provoke side effects not found with human hormone. Pharma companys prefer synthetic hormones which are patented while NATURAL BIO- IDENTICAL HORMONES are not .
Studys show women given synthetic Estrogen show 100 % risk of blood clots & stroke, 40% increase in heart attacks, 26 percent in breast cancer, compared to women in a control group who were give a placebo. Women who have been using natural , bioidentical Estrogen have not suffered these harmful effects. HORMONES MUST BE SUPERVISED BY A DOCTOR.

The above verbatim quote from the Edge Effect by Eric Braverman,MD.
Path-Medical Center NYC, Cabrini Hospital NYC.

HORMONES---- DEFINED AS/ HRT, HORMONE REPLACEMENT THERAPY

Ninety percent of all hormones are produced in or regulated by the brain. They are the brains messengers, which are sent to all other parts of the body to control the specific functions of cells And organs. Hormone Replacement Therapy can effectively alter brain chemical processes although not as quickly as perscription medications.
As we age, our hormone producing organs and glands begin to wear out. Their output drops, and the corresponding parts of the body begin to break down. The brain has to work harder, it tries to compensate for diminished body functions. If the decline in hormones is not treated, or treated improperly, these biochemicals will be reduced further resulting in more serious conditions. Hormonal impact on brain function is indisputable. Research studies clinical applications with thousands of patients demonstrated the postive effect that hormones have on neur-transmitter deficiency conditions, such as diminished concetration, memory loss, nicotine cravings, and insomnia.


The above quoted verbatim -- Eric Braverman, MD, The Edge Effect
Director of Path Medical Center NYC, Director of Alternative Medicine at Cabrenni Hospital NYC.

EXCITOTOXIN: DEFINED AS-------------------

Excitotoxin is defined as a substance added to foods and beverages that literally stimulates neurons to death, causing brain damage of varying degrees. They can be found in such ingredients as monosodium glutamate (MSG), aspartame (nutrasweet), cysteine, hydrolyzed protein, and aspartic acid.


The above are the thoughts quoted verbatim from the book, Excitotoxins the taste that kill. Authored by Russell L. Blaylock, MD. Neurosurgeon, Clinical Researcher.

VITAMIN D SUNLIGHT & TANNING BEDS

Supplements and diet, and not sunlight, should be your source of Vitamin D, Dermatology experts have concluded. U.K. researchers proposed 10 to 15 minuets unprotected sun exposure as a good source of vitamin D. Other researchers differ. Studies have shown that sunshine levels in some northern countries are so weak during winter months that the body makes no vitamin Dat all, leading some to estimate half of the population have insufficent or deficient levels of the vitamin, prompting some to recommend tanning beds. Researchers commented on societys where life expectancey has doubled & 30 % of caucasians will develop skin cancer. " Fortunately, there is a non-carcinogenic alternative -- intestinal absorption of vitamin D, fortified foods and / or dietary supplements". said researchers---- Wolpowitz and Gilchrest , Boston University Of Medicine

The afore mentioned source
The Journal of the American Academy of Dermatologists
( On - Line, doi: 10.1016/ J. Jaad. 2005.11.1057).
Deon Wolpowitz and Barbard Gilchrest.

CHOLECALEIFEROL, ERGOCALCIFEROL, IN THEORY----

vitamin D refers to two biologically inactive precursors - - D3, also known as Cholecalciferol, and D2, known as Ergocalciferol. The former is produced in the skin on exposure to UVB radiation (290 to 320 n m ) and can also be consumedfrom oily fish. The latter is derived from plants and only enters the body via the diet. Both D3 and D2 precursors are hydroxylated in the liver and kidneys to form 25- hydroxy vitamin D< the non-active "storage" form, , and 1,25 - dihydroxyvitamin D, the biologically active form that is tightly controlled by the body.


The above source is quoted from verbatim
a report from Decision News Media SAS.

NEW CONCEPTS IN MEICINE NOT COVERD IN THE MEDIA

Benign hypertrophy prostate, BHP, is not due to enlargement of the prostate as urologists claim The cause is Testosterone , thats the missing link, thats the exact statement from noted endocrinologist, Dr. Eugene Shippen. I am quoting an interview verbatim.

Dr.Shippen : Alot of the BHP ( Benign Prostate Hypertrophy) symptoms that we get are due to a loss of energy of the prostate muscles that open and close the doors and allow flow to be maximized. A lot of the BHP symptoms dont correlate at all with the size of the prostate. They correlate with testosterone. Once we make that link, men dont have to get up to urinate three times a night, there is a misconception among urologists that BHP is really due to enlargment of the prostate. Half of the men don't have an enlarged prostate, and the missing link is testosterone.

Interviewer : So as men lose their hormones, testosterone in this case, they lose their muscle tone not only outwardly, but internally as well ?

Dr. Shippens reply ----- Correct, bladder function, prostate function, sexual function, and tone in the muscles of the pelvis are all related to declining Testosterone levels and atrophy, they literally lose the athleticism of those muscles. (close quote )
The above interview I have noted verbatim, by Dr. Eugene Shippen U.S.A. leading endocrinologist, author and researcher, authority on Andropause.
Interviewer---- Suzane Somers.

HORMONES, BONES , CALCIUM, VITAMIN D, TETANY

PARATHYROID HORMONE DEFINED AS ------------------

Lying just above the thyroid are a variable number of bean- shapped glands known as the parathyroid, the primary function of the parathyroids is the maintenance of adequate levels of calcium in the extra cellular fluid. The most significant function of parathyroid hormone is mobilization of Calcium from bone, it reduces phosphate concentration, permitting more calcium to be mobilized. Hypoparathyroidism leads to manifestations of Hypocalcemia and Tetany, symptoms are muscle spasms, convulsions, gradual paralysis with dyspena &death from exhaustion prior to death gastrointestinal hemorrhages & hematemesis frequently occur.
The symptoms of tetany are relieved by administration of calcium salts. Calcium salts administered intravenously. Large doses of Vitamin Dare also useful to relieve tetany and restore the normal level of calcium in the blood.

The above is quoted verbatim from the textbook
Bergersen Pharmacology In Nursing Thirteenth Edition.

STRESS FRACTURES REDUCED BY VITAMIN D & CALCIUM SUPPLEMENTATION

Supplementing female military recruits with Vitamin D & calcium prevents stress fractures and debilitating overuse injuries. Sress fractures occur when bones are repetitively stressed over short periods of time without adequate time for repair, more common in women than men.
Researchers randomized 5,201 female Navy recurit volunteers to recieve 2,000 mg calcium and 800IU Vitamin D daily or placebo during eight weeks of basic training. During the treatment period,309 participants were diagnosed with stress fracture. Women who recieved calcium & Vitamin D had a 20% lower incidence of stress fracture than the placebo group.
Supplementing basic training recruits with Calcium & Vitamin D supplements may significantly reduce debility and financial costs releated to stress fractures.
Authors of study concluded------ Supplementation with Calcium & Vitamin D provides a safe, easy & inexpensive intervention that does not interfere with training goals".

The Peer- Review Journal cited above is---------
Lappe J, Cullen D, Haynatzki G, Recker R, Ahlf R, Thompson K.
Calcium and Vitamin D decreases incidence of stress fractures in Female Navy recruits. J Bone Miner Res. 2008 MAY: 25(5) : 741-9

VITAMIN D3, HORMONES,BONES ,AND ORGANS

The kidneys make a hormone called Calcitrol, a unique form of vitamin D. Vitamin D is in actuality not a vitamin but a type of steroidal hormone that is synthesized in a unique endocrine system in the body. During sunlight exposure the human skin converts a form of cholesterol to Vitamin D3 the liver alters or metabolizes this again (into 25- hydroxycholecalciferolaka 25-OHD3, then the kidneys use that altered substance to make two highly biologically active hormones. One of them Calcitriol, acts on the cells of the intestine to increase absorption of calcium from the diet and direct it to the bones for bone formation. Some of this calcium is also used to patch damaged blood vessels contributing to arteriosclerosis. Calcitriol also regulates certain parathyroid hormones that maintain the bodys level of phosphorus. The kidneys constantly monitor the levels of calcium and phosphorus in the body and increase or decrease them as needed. Through calcitrol the kidneys regulate bone mineralization and maintain the transfer of calcium to the bones to make them stronger. They effect not only the bone marrow in the creation of red blood cells but also the bone itself. Low androgen levels in men also have an impact on kidney function.

Source : Stephen Harrod Buhner, Herbalist and noted author of
Vital Man - Natural Health Care For Men at Midlife.

MEDICAL NOMENCLATURE

DEFINED AS----------

(1) BLOOD GLUCOSE: The main sugar found in the blood, glucose serves as the body's primary source of energy.

(2) DIABETIC NEUROPATHY : A nerve disorder caused by diabetes. This disorder leads to pain or loss of felling in the toee, feet, legs, hands or arms.

(3) ENDOCRINOLOGIST: A specialist in diseases and conditions of the glands (organs that male hormones) .

(4) FREE RADICAL : A highly reactive chemical that attacks molecules that are key to cell functioning, by capturing electrons and thus changing chemical structures.


(5) HORMONE : A chemical made by the glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or organs. Some hormones can also be made in laboratories.

(6) FUNCTIONAL FOOD: A food that has biologically active components ( such as Fish oils or plant estrogen) that may provide health benefits beyond basic nuttrition.

(7) HbAI C: Hemoglobin AIC , a blood test that measures a persons average blood glucose over a period of weeks or months.

(8) Ophthalmologist : A specialist in diseases and disorders of the eye.

(9) Podiatrist : A specialist in the care of the foot and treatment of foot disorders.

(10) Triglyceride : The form in which fat is stored in the body. High triglyceride levels in the blood may raise the risks for heart attack or stroke.

MEDICAL NOMENCLATURE

DEFINED AS----
Basic Science Study: A laboratory study done at the molecular level of biology and / orchemistry, to obtain necessary knowledge and background for later research such as animal studies and clinical trials.


CLINICAL TRIAL : A research study in which a treatment or therapy is tested in people to see
If it is safe and effective. Clinical trials are a key part of the process in finding out which treatments work, which do not and why, clinical trial results also contribute new knowledge about disease and medical condition.

CONTROLLED STUDY: A clinical trial in which one group recieves a treatment under study and another group ( the controll group ) recives either a placebo, standard treatment, or no treatment.

RANDOMIZED CLINICAL TRIAL : In a randomized clinical trial, each participant is assigned by chance ( through a computer or a table of random numbers) to one of two groups. The investigational group recieves the therapy, also called the active treatment. The control group receives either the standard treatment, if there is one for their disease or condition, or a placebo.

PLACEBO : An inert or sham treatment, such as a sugar pill.

LOW VITAMIN D LEVELS LINKED WITH DEPRESSION

Older people with low levels of Vitamin D and elevated levels of parathyroid, hormone (PTH, a hormone that regulates blood calcium levels) are more likely to be depressed than those with normal levels. This Dutch study, researchers measured levels of 25- hydroxyvitamin -D and PTH in 1,282 participants aged 65 to 95, of whom 26 were suffering from major depression and 169 from minor depression. They found 25-hydroxyavaitamin D to be 14% lower in depressed subjects ( average: 19 ng /ml.) In bth depressed and non- depressd participants, Vitamin D was far below optimal ranges of 50-60 ng/ml of 25 hydroxyvitamin D of blood indicative of how pervasive Vitamin D deficiencies have become.
Serum PTH levels were 33% higher in those with major depression compared with their non- depressed counterparts. Higher PTH can be caused by inadequate Vitamin D status.

The Peer Review Journal cited above is ------
Hoogendijk WJ, Lips P, Dik MG, Deeg Dj, Beekman AT, Pennix BW,
Depression is associated with Decreased 25-hydroxyvitamin D and Increased parathyroid hormone levels in older adults.
ARCH GEN PSYCHIATRY. 2008 MAY: 65 (5) : 508-12.

VITAMIN D DEFICIENCY IS COMMON, EVEN IN SUNNY CLIMATE, IN USA

Individuals who live in sunny climates are at risk of Vitamin D deficiency, Researchers analyzed serum levels of 25- hydroxy vitaminD in 637 residents of southern Arizona, Vitamin D deficiency which was defined as 25-hydroxyvitamin D below 20 ng/ml (50 nmol/ L) , was found in 25% of the residents. Many scientists now believe that optimal Serum levels of 25- hydroxyvitamin Dare within the range of 30-50 ng/ ML (75-125 nmol/ l. Deficiency of VitaminD in residents of a sunny region is a significant public health concern because, " Recent work has associated suboptimal concentration of circulating 25- hydroxyvitamin D with a number of diseases".

Peer review Journal cited above is ---------
Grant WB, Holick MF, Benefits and reqirements of Vitamin Dfor Optimal Health : A review. ALTERN MED REV>2005 JUN, 10(2) :94-111.

STUDY, VITAMIN D INSUFFICIENCY, BREAST CANCER

Study finds high incidence of Vitamin D- insufficiency in Women diagnosed with breast cancer.
Published article in the July 20008: issue of the American Journal of Clinical Nutrition, Scientists at the Fred Hutchinson Cancer Research Center in Seattle, the National Cancer Institute, and other research centers report a high incidence of vitamin D insufficency among female breast Cancer survivors. Data obtained from 790 participants in the multi- ethnic Health, Eating, Activity, and Lifestyle (HEAL) study of breast cancer patients, which sought to determine the effect of diet, hormones and other factors on breast CANCER PROGNOSIS AND SURVIVAL.
Blood samples collected within three years following the participants breast cancer diagnosis were analyzed for Serum 25 - hydroxy vitamin D levels, the primary biomaarked used to evaluate Vitamin D status. Dietary questionnaires were used to obtain information concerning Vitamin D intake levels from foodand supplements. Few women were found to have levels of Vitamin D of at least 32 nanograms per milliliter, that are sufficent for optimal health. Deficient levels of Vitamin D were detected in 75.6 percent of the participants, Women who had been diagnosed with localized or regional breast cancer had lower Vitamin D levels than those with in situ ( noninvasive) disease only a quarter of the women reported using supplements. Authors note evidence suggests an asssociation between Vitamin D status and survival in breast cancer

Vitamin D therapy could be useful, cost effective treatment for breast cancer patients. The authors of this study write " Clinicians may want to consider testing their breast cancer patients for serum 25- hydroxy vitamin D and to offer appropriate recommendations, if necessary , to improve Vitamin D status".

Peer review Journal cited from---- July 2008, American Journal of Clinical Nutrition.
note Lifeexstension Magazine wwww.lef.org

TRIBULUS TERRESTRIS

Every man older than 35 years should get appropiate blood tests such as ------
total Testosterone/ Free Testosterone/ Estradiol/ PSA TEST/ DHEA/ HOMOCEYSTINE/
Every older mans goal --- Opimizing male hormone levels, effectivness of natural supplements are according to researchers safely support optimal hormone levels. Low Testosterone is a warning alarm, leading to ill health.
Tribulus Terrestris is a naatural herb that restores Testosterone and restores the urinary system.



Jared Breed
Free - Lance- Genuis

NATURAL TESTOSTERONE PLAN

Endocrine disruptors are awash in the world, in pollutants, they wreak havock on the reproductive system. Testosterone levels in men are in sharp decline world wide.
I believe a natural herb is the answer to this deliema, TRIBULUS TERRESTRIS,
This natural herb helps male libido and tone the urinary system its a form of testosterone.
Dr.Eric Braverman recomends this as an alternative to ANDRO- GEL, the natural perscription
Hormone replacement.

Stephen H. Buhner , his book The Natural Testosterone Plan.

NATURAL TESTOSTERONE

Endocrine disruptors are pesticides, ddt, chemicals in food and water , they effect the body in low levels, pollutants impact on all hormones, testosterone in particular", statment emmanates from
Rebecca Sutton PHD, researcher from non-profit, Environmental Working Group-- (www.ewg.org) One in every 4 men over 30 years old may have low testosterone levels.
Harmful bisophenol A- in cannned food lining and hard plastic/ the female hormone estrogen found in birth control pills, disrupts hormones particullary.


Rebecca Sutton PHD, www.ewg.org

THE VITAMIN D CURE, Dr. Dowd

VITAMIN D IS A HORMONE from the same family of steroid hormones as estrogen, progesterone, testosterone and cortisol.
VITAMIN D REGULATES GENE EXPRESSION IN THE NUCLEUS OF A CELL.
IT DOES NOT HAVE A FRONT ROW SEAT IN REGULATING OUR BIOCHEMISTRY,
ITS CONDUCTING THE ORCHESTRA.


SOURCE: JAMES DOWD , MD.

TESTOSTERONE IS KEY THAT UNLOCKS PROSTATE DISEASE

High levels of Testosterone men had least Prostate enlargment. The Prostate is designed to recive an influx of tesoserone its no coincidence that prostate disease occurs in a mans life in his later years just when the the sex hormone levels of tesosterone are in decline.
As men age there is an increase of estrogen and a decrease of testosterone that equals disaster.
BHP and Prostate Cancer occur when a mans levels of Testosterone are low and in decline, Testoterone is the source of the problem of prostate suffering.

The American Foundation for Urologic Disease estimates that more than half of all men fifty and older have enlarged prostates. Symptoms of BPH (1) Decreased force of urination (2) trouble initiating urination (3) dribbling ( trouble shutting off the urine stream (4) painful urination and frequent need to urinate / (5) Need to urinate at nighttime ( nocturia)

Source book----- Testosterone Syndrome Dr. Eugene Shippen

VITAMIN D, SLEEP SOUNDLY WITH D3

For optimal sleep take vitamin D3 2,000, to 5,000 I.U. international units, daily.

Above upon recomendation of DR. Edward Lichten. www.usdoctor.com

Taking 2,000 to 5,000 I.U. of D3daily, toxicity is rare and serum D blood samples can be followed until an adequate level is reached.

Dr. E. Lichten source---- Textbook of Bioidentical Hormones.

# 12 ESTROGEN LEVELS IN A MANS BLOOD TEST NOTED

View Life Extension's Male Hormone Modulation Protocol www.lef.org/ male Hormones.


The role that estrogen plays in mens health is the subject of todays medical conferences testing ones estradiol level is critical , it can be a serious problem if its to high or if its to low. Scienists are debating what the optimal levels of estrogen should be in men, proper blood testing and awareness can only thwart further suffering in men.

2007 STUDT , OLDER MEN, BPH, ESTRADIOL, DHT RESULTS, CONTINUED

lIFE EXSTENSION MAGIZINE , editoral in 1994 spoke of estrogen's role in (BPH ) encouraged men to take nutrients and the drugs ARIMIDEX & AVADART that exhibit anti- estrogen and anti- DHT properties in the prostate gland, itself.
When Estrogen & DHT are lowered in the blood, Prostate cells can compensate by synthesizing them in the prostate gland . Men also use nutrients that have aromatase- inhibiting properties.
Peer Review Journal cited above is -----------

Rohrmann S, Nelson Wg, Rifai N, et al.

Serum sex steroid hormones and lowering urinary tract symptoms in THIRD NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY ( NHANES 3) UROLOGY. 2007 APR; 69 (4) : 708-13

THE 2007 STUDY OF OLDER MEN, BPH URINARY TRACT , ESTRADIOL & DHT RESULTS

2007 Study, Researchers evaluated the association of sex hormone levels in the blood with common BPH urinary tract symptoms.
260 men, 60 years of age and older, blood levels of Testosterone, ESTRADIOL and other sex hormones measured, 128 cases had 2 of four symptoms ( excessive urination at night, hesitancy, incomplete emptying, and weak stream ) the 132 men in control group had no urinary symptoms. Results showed that BHP suffers had statistically significnatly greater estradiol concentrations tan symptom free controls. BHP suffers had a higher levels of marker for a metabolite for dihydrotestosterone ( DHT another documented factor in the development of BHP ). Men with greater estradiol concentration had a 1. 78 times higher incidence of urinary tract symptoms. A greater incidence of urinary tract symtoms occured in men with the highest levels of dihydrotestosterone metabolite, wheras blood testosterone level showed no effect on urinary symptoms. Doctors quoted as saying this study----------

" In this cross - sectional study represenative of older U.S.A. men , circulating AAG , a metabolite of dihyrotestosterone, and Estradiol were associated with an increased risl of having lower urinary tract symptoms ". (endquote )

#11 ESTROGENS ROLE IN BPH CONTINUED

# 11

Estrogen stimulates proliferation of stromal cells in the prostate gland that cause the urinary discomforts. A 2008 study documents specific mechanism by which estradiol causes rapid proliferation of prostate stromal cells. Researchers concluded these findings support the hypothesis that estrogen plays a role in the pathogensis of BPH, a disease charaterized predominantly by stromal overgrowth.

Peer Review Journal quoted from ------------

OESTROGEN AND BPH : EFFECTS ON STROMAL CELL PROLIFERATION AND LOCAL FORMATION FROM ANDROGEN.
J ENDOCRINOL. 2008 JAN; 197 (3) 483- 91

# 11 ESTROGENS ROLE IN BENIGN PROSTATIC HYPERPLASIA (BPH)

Estrogens role in prostate cancer, it;s role in BPH is clearly defined. A large body of human research confirms the inital findings.


OESTROGEN AND BENIGN PROSTATE HYPERPLASIA : EFFECTS ON STROMAL CELL PROLIFERATION AND LOCAL FORMATION FROM ANDROGEN. J ENDOCRINOL, 2008 JUNE 197 (3); 4833-91

THE PARADOX, ESTROGEN, PROSTATE CANCER

The carcinogenic effects of estrogen within the prostate gland. Excess estrogen can first damage DNA regulatory genes to cause cancer and then act as a prostate cancer suppressor.
In like manner excess estrogen damages prostate cell DNA to initate cancer, then acts as a temporary prostate cancer suppressor, THE PARADOX ESTROGEN SUPRESSES CANCER CELL PROPAGATION CAN ALSO CAUSE CANCER. LOOK AT TEST OF AGING MEN'S ESTRADIOL AND FREE TESTOSTERONE BLOOD LEVELS AS A POTENTIAL INDICATOR OF PROSTATE CANCER.
Aging men with low free testosterone and high estradiol often have prostate cancer. Based on these oobservations, many of these men will die from vascular disease possible cause by high Estrogen levels) before their prostate cancer is diagnosed. Men who suffered from estrogen overload early in life are expected to die sooner, and not live long enough to develop clinically diagnosed prostate cancer. LOOKING AT STATISTICAL STANDPOINT IT WOULD APPEAR THAT HIGHER ESTRADIOL LEVELS IN AGING MEN DO NOT RESULT IN GREATER INCIDENCES OF PROSTATE CANCER, SINCE MANY MEN WITH THE HIGHEST ESTROGEN LEVELS ARE NOT ALIVE TO PARTICIPATE IN THE STUDY. THEY DIE OF HEART DISEASE PRIOR TO SLOW MOVING PROSTATE DISEASE

# 10 ESTROGEN AND PROSTATE CANCER

# 10.

The role of estrogen in maligant prostate disease is contradictory and complex.
Studies indicate that estrogen is a cause of prostate cancer, yet when prostate cancer develops, certain estrogen compounds have anti - cancer effects.

Peer Review Journal cited ------------

A potential paradox in prostate adeno carcinoma progression : oestrogen as the initating driver.
Eur J CANCER, 2008 MAY: 44 (7) : 928 -36

#9 ESTRADIOL, HEART ATTACK

#9

A study on men admitted in hospital with acute heart attacks levels of sex hormones were evaluated. ESTRADIOL LEVELS OF HEART ATTACK PATIENTS WERE 180 % WHILE BIOAVILABLE TESTOSTERONE levels were 3% less than those of control patients.
Findings reveal higher heart attack incidence associated with high estrogen and low Testosterone, its possible that these low levels of testosterone and high levels of estradiol occured in response of the heart attack itself ".


Peer review Journal cited---------------

Bio- available testosterone levels fall acutely following myocardial infarction in men: association with Fibrinolytic factors , Endocr Res. 2002 Aug; 28 (3 ): 161-73

# 8 THE LETHAL MECHANISM OF EXCESS ESTROGEN.

# 8
The number one cause of death in persons over age 50 is the development of abnormal blood clot ( thrombus ) in an artery that blocks blood flow to the heart, lungs, and brain. Elevated estrogen predisposes people to these lethal thrombotic events men admitted to hospital with myocardial infarcts have elevated estradiol and low testosterone levels.

The Peer review journal cited--------------------
Tripathi L , Hegde BM. serum Estradiol and Testosterone levels following acute myocardial infarction in men. Indian J Physiol Pharmacol. 1998 Apr; 42 (2) :291-4.

# 8 THE LETHAL MECHANISM OF EXCESS ESTROGEN.

# 7 HIGH ESTRADIOL LEVELS SEEN IN MALE CHRONIC INFLAMATION PATIENTS.

# 7
Rheumatoid arthiritis a severe chronic inflammatory state results in increased risk of heart attack, cancer and stroke, this study of men with Rheumatoid Aarthritis evaluated blood levels of sex hormones compared with healthy controls.

The Peer- Review Journal cited from is ---------------------

Tengstrand B, Carlstrom K, Fellander- Tsai L, Hafstrom I. Abnormal levels of Serum dehydroepiandrosterone, estrone, and estradiol in men with rheumatoid arthritis : high correlation between Serum estradiol and current degree of inflamation.

J RHEUMATOL. 2003 NOV; 30 (11 ) :2338- 43

# 6 TESTOSTERONE, CARDIC,ESTRADIOL, AGING MALE.

#6
Men with coronary atherosclerosis had a low testosterone, higher levels of ESTRONE ( another potent estrogen), and a low level of testosterone in the pressence of a high level of Estradiol.
"Low levels of total Testosterone, Testosterone / Estradiol ratio and free androgen index and higher levels of Estrone in men with Coronary Artery Disease appear together with many features of metabolic syndrome and may be involved in the pathogenesis of coronary atherosclerosis">


The Peer review Journal cited is---------------------

Dunajska K, Milewicz A, Szymczak J, et al. Evaluation of sex hormones levels and some metabolic factors in men with coronary atherosclerosis in the aging male. 2004 Sep: 7 (3) :197-204.

# 5 WHY THE EXCESS ESTRADIOL IN MEN ?

# 5 The reason men suffer from excess estradiol and deficient testosterone is their aging blood produce less testosterone while more of their beneficial testosterone is converted ( aromatized) into Estradiol. The Pathological result in altering the ratio of testosterone to estrogen, creating estrogen dominance. This imbalance of estrogen overload and testoterone insuffciency is an often overlooked cause of cardiovascular disease. Thank God, There are safe methods to block the aromatase enzyme in order to lower excess estrogen while boosting free testosterone levels.


The study reflecting Estradiol------ take note of ---

Vermeulen A, Kaufman JM, Goemaere S, vanPottelberg, I.
estradiol in elderly men: Evaluation of sex hormone levels and some Metabolic factors in men with coronary atherosclerosis. Aging Male. 2004 Sep; 7 (3) : 197 -204.

#4 ESTRADIOL HIGHER IN MALE HEART ATTACK VICTIMS

#4 Estradiol higher in male heart attack victims/
This study compared blood levels of testosterone and estradiol in men suffering acute myocardial infarction ( heart attack) with those who had previously suffered a heart attack.
Sex hormones measured in patients presenting with acute heart attack, patients presenting with acute heart attack, patients with old heart attack, and patients with normal coronary arteries.
The results------- showed significantly higher levels of estradiol in both groups of heart attack patients compared with those without coronary disease. NUMEROUS PRIOR STUDIES, HEART ATTACK VICTIMS ALSO HAD DECREASED TESTOSTERONE LEVELS.


The study quoted from above is -------

Mohamed MJ, HAIRI A, Hader AA, Serum Levelsof sex Hormones Neuro Endocrinol lett.
2007 Apr; 28 (2) : 182-6.

#3 ESTRADIOL, CAROTID ARTERY, STROKE.

To evaluate the arterial system you must measure the inner and medial wall of the carotid artery using a ultrasound test. In a 2006 study published, blood levels of estradiol were measured in 313 men average age 58. Carotid artery intima- media thickness measured at baseline and then three years lateer. Men with higher levels of estradiol suffered a worsening thickening of their carotid artery wall. Researchers concluded " circulating estradiol is a predictor of progession of carotid artery intima - media thickness in middle age men">


Kindky nite the study that proposed this ---------------------

Tivesten A, Hulthe J, Wallenfeldt K, et al. Circulating estradiol is an independent predictor of progression of carotid artery intima- media thickness in middle - aged men.
J Clin Endocrinol Metab. 2006 Nov; 91 ( 11) : 4433-7.

This study of middle - aged men based on findings that treatment of men with Prostate Cancer using orally ingested estrogen drugs is associated with increased cardiovascular events and deaths. Ultrasound measurements of carotid artery wall provides an accurate prognostic indicator of arterial disease.
Findings of this study show progression of carotid artery intima - media thickness in men with higher estradiol levels. Greater Carotid artery intima- media thickness sharply correlates with increased risks of heart disease and stroke.

#2 STROKE ESTRADIOL AND OLDER MEN

In this research study blood levels of estradiol ( a potent estrogen) were measured in 2,197 men aged 71 to 93 years , men with the highest blood levels of estradiol had a 2.2 fold greater risk of stroke compared with those whose estradiol levels were lower. This research study is

Abbot RD, Launer LJ, Rodriquez, BL, et al. Serum estradiol and the risk of stroke in elderly men. Neurology, 2007 Feb 20; 68 (8) : 563-8.


This study revealed that estradiol blood levels greater than 34.1 Pg/ ML resulted in this more than doubling of stroke incidence.
Life Extension magizine warned years ago , men keep your estradiol levels below 30 pg/ ml, this recent stroke study clearly validates our prior recommendation

DANGERS OF EXCESS ESTROGEN IN THE AGING MALE 13 INSTALLMENTS.

DANGERS OF EXCESS ESTROGEN IN THE AGING MALE - 13 INSTALLMENTS
SOURCES---- lIFE EXSTENSION MAGIZINE 2008, William Faloon
#1.

Stroke is the third leading cause of death , abnnormal blood clotting in the cerbral blood vessels, the most common cause of stroke.
Excess Estrogen promotes abnormal blood clots: the source of research for this claim is



Colmou A. Estrogens and Vascular Thrombosis. Soins Gynecol Obstet Pueric Pediatr. 1982 Sep. (16) : 39-41

ESTROGEN METABOLISM, IT TURNS ESTRADIOL INTO ESTRONE .

Vitamin D and estrogen metabolism it turns estradiol into estrone, D3 diffuses its harmful effects. Vitamin D, which has been shown to have an effect on estrogen metabolism in a different way. It turns estradiol (a hormone) back into estrone, which is the weak estrogen. When that system is working, the body has the ability to regulate estrogen according to its needs, instead of being overdriven toward the more powerful estrogen, estradiol.


INTERVIEWER------ I did not realize that DR. Shippen.

Dr. Eugene Shippen reply ---- Yes, it also has the ability to induce cells that are becoming cancerous to self- destruct, plus it has anti- inflammatory effect.
Vitanin D when taken in adequate doses protects bones from osteopororosis. It has anti- cancer effects. Its influence on estrogen metabolism and its ability to induce cancer cells to self destruct."

Verbatim interview with DR. Eugene Shippen Endocrinologist, Researcher, Author.